I often find myself reading about a gene and then wondering if it is on the Lifecode reports. There are so many genes that I decided to create a table and so this is an alphabetical directory.
The reports below are useful for you to look at and my reports and are used throughout the course as examples.
Metabolics Report
Athletes Report – not used.
Genes by report Lifecode Index
This table is a central lookup for the genes we can test with lifecode – it is not all nutrigenetics genes! You will find:
- The Lifecode GX reports in which the gene appears
- The gene’s primary nutrigenetic system (one of the eight core systems, plus a cofactor category)
- The conditions this gene influences in practice
Use the search function or scroll alphabetically to find a gene. This helps you check where to read more about that gene inside the full reports.
Please note that some genes appear in more than one report.
| ACE |
| Reports: Hormones, Metals and Minerals Report, Nervous System, Nutrient Core Primary System: Inflammation & Immune System Conditions: Hypertension, Hypertension (Sodium/Potassium sensitivity) |
| ADH1B |
| Reports: Detoxification Primary System: Liver Conjugation Conditions: Alcohol Sensitivity |
| ADH1C |
| Reports: Detoxification Primary System: Liver Conjugation Conditions: Alcohol Sensitivity |
| ADORA2A |
| Reports: Detoxification, Nutrient Core Primary System: Neurotransmitters Conditions: Caffeine Sensitivity |
| ADRB1 |
| Reports: Hormones, Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Chronic Stress, Hypertension |
| ADRB2 |
| Reports: Hormones, Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Chronic Stress, Hypertension, Sleep Disorders |
| AGT |
| Reports: Hormones, Metals and Minerals Report, Nutrient Core Primary System: Inflammation & Immune System Conditions: Hypertension, Hypertension (Sodium/Potassium sensitivity), Insulin Resistance & Metabolic Syndrome |
| AGTR1 |
| Reports: Hormones, Metals and Minerals Report, Nutrient Core Primary System: Inflammation & Immune System Conditions: Hypertension (Sodium/Potassium sensitivity) |
| ALDH2 |
| Reports: APOE, Detoxification, Histamine Intolerance, Nutrient Core Primary System: Liver Conjugation Conditions: Alcohol Sensitivity, Bowel Cancer Prevention, Gut Health (General), Histamine Intolerance |
| ALPL |
| Reports: Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Anxiety, GABA Imbalance, Migraine |
| APOE |
| Reports: APOE, Detoxification, Nervous System, Nutrient Core Primary System: Glutathione & Redox Conditions: Alzheimer’s Disease (Atrophic subtype), Alzheimer’s Disease (General Risk), Alzheimer’s Disease (Inflammatory subtype), Bowel Cancer Prevention, Chronic Inflammation (Neurological), Cognitive Decline & Neurodegeneration, Gut Health (General), Heavy Metal & Mould Toxicity, Insulin Resistance & Metabolic Syndrome |
| AS3MT |
| Reports: Detoxification, Metals and Minerals Report, Methylation Primary System: Liver Conjugation Conditions: Cancer Risk & Toxicity (Arsenic sensitivity) |
| ASMT |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: Serotonin Imbalance, Sleep Disorders |
| ATP2B1 |
| Reports: Metals and Minerals Report Primary System: Other / Cofactors & Transport Conditions: Osteoporosis & Bone Health (Calcium sensitivity) |
| ATP7B |
| Reports: Metals and Minerals Report Primary System: Glutathione & Redox Conditions: Wilson’s Disease (Copper overload) |
| BCO1 |
| Reports: Nutrient Core, Thyroid Health Report Primary System: Other / Cofactors & Transport Conditions: Thyroid Hormone Activation, Vitamin A Deficiency |
| BDNF |
| Reports: APOE, Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Alzheimer’s Disease (Atrophic subtype), Alzheimer’s Disease (General Risk), Cognitive Decline & Neurodegeneration |
| BHMT |
| Reports: APOE, Detoxification, Hormones, Methylation Report, Nutrient Core Primary System: Methylation Conditions: Methylation Efficiency & Homocysteine Management |
| CAPZB |
| Reports: Thyroid Health Report Primary System: Thyroid Conditions: Thyroid Health (General & HPT Axis Regulation) |
| CASR |
| Reports: Metals and Minerals Report Primary System: Other / Cofactors & Transport Conditions: Osteoporosis & Bone Health (Calcium sensitivity) |
| CBS |
| Reports: APOE, Detoxification, Hormones, Methylation Report, Nutrient Core Primary System: Methylation Conditions: Methylation Efficiency & Homocysteine Management |
| CD40 |
| Reports: Hormones, Nutrient Core, Thyroid Health Report Primary System: Inflammation & Immune System Conditions: Thyroid-Related Inflammation |
| CNR1 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: GABA Imbalance, Glutamate Imbalance |
| CLOCK |
| Reports: Nutrient Core Primary System: Neurotransmitters Conditions: Circadian Rhythm Issues |
| COL1A1 |
| Reports: Nutrient Core Primary System: Other / Cofactors & Transport Conditions: Collagen Formation Issues |
| COMT |
| Reports: APOE, Detoxification, Hormones, Methylation Report, Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: ADHD & Neurotransmitters, Addiction & Impulsivity, Anxiety, Bowel Cancer Prevention, Chronic Stress, Depression & Low Mood, Dopamine Imbalance, Histamine Intolerance, Hypertension, IBS (Irritable Bowel Syndrome), Impaired Methylation & Homocysteine Management, Inflammation & Mood, Migraine, Poor Methylation |
| CYP19A1 |
| Reports: Detoxification, Hormones Primary System: Liver Conjugation Conditions: Oestrogen Dominance |
| CYP1A1 |
| Reports: Detoxification Primary System: Liver Conjugation Conditions: Bowel Cancer Prevention, PAHs & Pollution Detox, Pesticide & Chemical Sensitivity, Mould & Mycotoxin Detox |
| CYP1A2 |
| Reports: Detoxification, Nutrient Core Primary System: Liver Conjugation Conditions: Bowel Cancer Prevention, Caffeine Sensitivity, Gut Health (General), Mould & Mycotoxin Detox, PAHs & Pollution Detox, Pesticide & Chemical Sensitivity |
| CYP1B1 |
| Reports: Detoxification, Hormones Primary System: Liver Conjugation Conditions: Bowel Cancer Prevention, Oestrogen Dominance, PAHs & Pollution Detox, Pesticide & Chemical Sensitivity |
| CYP2C19 |
| Reports: Detoxification Primary System: Liver Conjugation Conditions: Medication Detoxification & Sensitivity |
| CYP2C9 |
| Reports: Detoxification Primary System: Liver Conjugation Conditions: Medication Detoxification & Sensitivity, NSAID Sensitivity |
| CYP2D6 |
| Reports: Detoxification Primary System: Liver Conjugation Conditions: Medication Detoxification & Sensitivity |
| CYP2E1 |
| Reports: Detoxification Primary System: Liver Conjugation Conditions: Alcohol Sensitivity, Paracetamol Sensitivity |
| CYP3A4 |
| Reports: Detoxification, Hormones Primary System: Liver Conjugation Conditions: Mould & Mycotoxin Detox, Oestrogen Dominance |
| DAO |
| Reports: Detoxification, Histamine Intolerance, Nutrient Core, Nervous System, Hormones, APOE Primary System: Gut–Microbiome Conditions: Gut Health (General), Histamine Intolerance, IBS (Irritable Bowel Syndrome) |
| DIO1 |
| Reports: Thyroid Health Report, Nutrient Core Primary System: Thyroid Conditions: Thyroid Hormone Activation |
| DIO2 |
| Reports: Thyroid Health Report, Nutrient Core Primary System: Thyroid Conditions: Thyroid Hormone Activation |
| DRD2 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: ADHD & Neurotransmitters, Addiction & Impulsivity, Anxiety, Cognitive Decline & Neurodegeneration, Cognitive Function (Memory), Depression & Low Mood, Dopamine Imbalance |
| ESR1 |
| Reports: Hormones Primary System: Other / Cofactors & Transport Conditions: Oestrogen Dominance |
| ESR2 |
| Reports: Hormones Primary System: Other / Cofactors & Transport Conditions: Oestrogen Dominance |
| FADS1 |
| Reports: Nutrient Core Primary System: Glutathione & Redox Conditions: Essential Fatty Acid Issues |
| FADS2 |
| Reports: Nutrient Core Primary System: Glutathione & Redox Conditions: Essential Fatty Acid Issues |
| FAAH |
| Reports: Nervous System, Detoxification Primary System: Neurotransmitters Conditions: ADHD & Neurotransmitters, Addiction & Impulsivity, Anxiety, GABA Imbalance, Glutamate Imbalance, Pain Sensitivity, Paracetamol Sensitivity, Sleep Disorders |
| FCRL3 |
| Reports: Thyroid Health Report Primary System: Inflammation & Immune System Conditions: Thyroid-Related Inflammation |
| FKBP5 |
| Reports: Hormones, Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Anxiety, Chronic Stress, Depression & Low Mood, Inflammation & Mood, Thyroid Health (General & HPT Axis Regulation) |
| FTO |
| Reports: Nutrient Core, Hormones Primary System: Other / Cofactors & Transport Conditions: High Appetite & Weight Gain, Insulin Resistance & Metabolic Syndrome |
| FUT2 |
| Reports: APOE, Detoxification, Methylation Report, Nutrient Core Primary System: Gut–Microbiome Conditions: Bowel Cancer Prevention, Folate Metabolism Issues, Gut Health (General), IBS (Irritable Bowel Syndrome), Methylation Efficiency & Homocysteine Management, Vitamin B12 Deficiency |
| GABRA2 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: ADHD & Neurotransmitters, Anxiety, GABA Imbalance |
| GAD1 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: GABA Imbalance, Glutamate Imbalance |
| GAD2 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: GABA Imbalance, Glutamate Imbalance |
| GC |
| Reports: Nutrient Core, Thyroid Health Report Primary System: Other / Cofactors & Transport Conditions: Thyroid Hormone Activation, Thyroid-Related Inflammation, Vitamin D Deficiency |
| GPX1 |
| Reports: Detoxification, Metals and Minerals Report, Thyroid Health Report Primary System: Glutathione & Redox Conditions: Histamine Intolerance, Hypothyroidism (Selenium deficiency), Reactive Oxygen Species (Oxidative Stress) |
| GPX4 |
| Reports: Detoxification, Metals and Minerals Report, Thyroid Health Report Primary System: Glutathione & Redox Conditions: Hypothyroidism (Selenium deficiency) |
| GSTM1 |
| Reports: APOE, Detoxification, Histamine Intolerance, Nutrient Core Primary System: Glutathione & Redox Conditions: Alzheimer’s Disease (General Risk), Alzheimer’s Disease (Toxic subtype), Bowel Cancer Prevention, Glutathione Detoxification, Gut Health (General), Heavy Metal & Mould Toxicity, Medication Detoxification & Sensitivity, Mould & Mycotoxin Detox, PAHs & Pollution Detox, Paracetamol Sensitivity, Pesticide & Chemical Sensitivity, Impaired Methylation & Homocysteine Management, Mercury Toxicity & Sensitivity |
| GSTP1 |
| Reports: APOE, Detoxification, Histamine Intolerance, Nutrient Core Primary System: Glutathione & Redox Conditions: Alzheimer’s Disease (General Risk), Alzheimer’s Disease (Toxic subtype), Bowel Cancer Prevention, Glutathione Detoxification, Gut Health (General), Heavy Metal & Mould Toxicity, Medication Detoxification & Sensitivity, Mercury Toxicity & Sensitivity, Mould & Mycotoxin Detox, PAHs & Pollution Detox, Pesticide & Chemical Sensitivity, Impaired Methylation & Homocysteine Management, Oestrogen Dominance, Paracetamol Sensitivity |
| GSTT1 |
| Reports: APOE, Detoxification Primary System: Glutathione & Redox Conditions: Alzheimer’s Disease (General Risk), Alzheimer’s Disease (Toxic subtype), Bowel Cancer Prevention, Gut Health (General), Heavy Metal & Mould Toxicity, Medication Detoxification & Sensitivity, Mercury Toxicity & Sensitivity, Mould & Mycotoxin Detox, PAHs & Pollution Detox, Paracetamol Sensitivity, Pesticide & Chemical Sensitivity, Impaired Methylation & Homocysteine Management |
| HFE |
| Reports: Metals and Minerals Report Primary System: Glutathione & Redox Conditions: Iron-deficiency Anaemia (modulates iron handling – clinical context dependent) |
| HLA-DQA1 |
| Reports: Thyroid Health Report Primary System: Inflammation & Immune System Conditions: Autoimmune Thyroid Conditions (Hashimoto’s & Graves’ Disease) |
| HLA-DQB1 |
| Reports: Thyroid Health Report Primary System: Inflammation & Immune System Conditions: Autoimmune Thyroid Conditions (Hashimoto’s & Graves’ Disease) |
| HNMT |
| Reports: Histamine Intolerance, Nutrient Core, Detoxification, Nervous System Primary System: Gut–Microbiome Conditions: Gut Health (General), Histamine Intolerance, IBS (Irritable Bowel Syndrome) |
| HTR1A |
| Reports: Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Anxiety, Depression & Low Mood, Gut Health (General), IBS (Irritable Bowel Syndrome), Migraine, Pain Sensitivity, Serotonin Imbalance |
| HTR2A |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: Serotonin Imbalance |
| IFNG |
| Reports: APOE, Nervous System, Nutrient Core Primary System: Inflammation & Immune System Conditions: Alzheimer’s Disease (General Risk), Bowel Cancer Prevention, Chronic Inflammation (Neurological), Depression & Low Mood, Gut Health (General), Inflammation & Mood |
| IL6 |
| Reports: Thyroid Health Report, Nutrient Core Primary System: Inflammation & Immune System Conditions: Thyroid-Related Inflammation |
| KL |
| Reports: Metals and Minerals Report Primary System: Other / Cofactors & Transport Conditions: Phosphorus Regulation Issues |
| LEPR |
| Reports: Nutrient Core, Hormones Primary System: Other / Cofactors & Transport Conditions: High Appetite & Weight Gain, Insulin Resistance & Metabolic Syndrome |
| MAOA |
| Reports: Nervous System, Detoxification, Nutrient Core, Hormones Primary System: Neurotransmitters Conditions: ADHD & Neurotransmitters, Anxiety, Depression & Low Mood, Dopamine Imbalance, Histamine Intolerance, IBS (Irritable Bowel Syndrome), Migraine, Serotonin Imbalance, Sleep Disorders |
| MAOB |
| Reports: Nervous System, Detoxification Primary System: Neurotransmitters Conditions: Dopamine Imbalance, Histamine Intolerance |
| MTHFR |
| Reports: APOE, Detoxification, Histamine Intolerance, Methylation Report, Nutrient Core, Hormones Primary System: Methylation Conditions: ADHD & Neurotransmitters, Alzheimer’s Disease (Atrophic subtype), Alzheimer’s Disease (General Risk), Alzheimer’s Disease (Inflammatory subtype), Bowel Cancer Prevention, Cancer Risk & Toxicity (Arsenic sensitivity), Chronic Inflammation (Neurological), Cognitive Decline & Neurodegeneration, Cognitive Function (Memory), Depression & Low Mood, Folate Metabolism Issues, Gut Health (General), Histamine Intolerance, IBS (Irritable Bowel Syndrome), Impaired Methylation & Homocysteine Management, Inflammation & Mood, Migraine, Methylation Efficiency & Homocysteine Management, Poor Methylation, Vitamin B12 Deficiency |
| MT1A |
| Reports: Metals and Minerals Report, Detoxification Primary System: Glutathione & Redox Conditions: Heavy Metal Toxicity (Metallothionein dysfunction) |
| MT2A |
| Reports: Metals and Minerals Report, Detoxification Primary System: Glutathione & Redox Conditions: Heavy Metal Toxicity (Metallothionein dysfunction) |
| MTNR1B |
| Reports: Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Serotonin Imbalance, Sleep Disorders |
| NAT2 |
| Reports: Detoxification, Histamine Intolerance Primary System: Liver Conjugation Conditions: Histamine Intolerance, Medication Detoxification & Sensitivity, NSAID Sensitivity, Paracetamol Sensitivity |
| NQO1 |
| Reports: Detoxification Primary System: Glutathione & Redox Conditions: PAHs & Pollution Detox, Reactive Oxygen Species (Oxidative Stress) |
| OPRM1 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: Addiction & Impulsivity, Dopamine Imbalance, Pain Sensitivity |
| PDE8B |
| Reports: Thyroid Health Report Primary System: Thyroid Conditions: Thyroid Health (General & HPT Axis Regulation) |
| PEMT |
| Reports: Methylation Report, Nutrient Core, APOE, Detoxification, Hormones Primary System: Bile & PEMT Conditions: Methylation Efficiency & Homocysteine Management |
| PGC1A |
| Reports: Nutrient Core, Hormones Primary System: Other / Cofactors & Transport Conditions: Sugar & Fat Metabolism |
| PNMT |
| Reports: Nervous System, Hormones Primary System: Neurotransmitters Conditions: Hypertension |
| PON1 |
| Reports: Detoxification Primary System: Glutathione & Redox Conditions: Pesticide & Chemical Sensitivity |
| PTPN22 |
| Reports: Thyroid Health Report Primary System: Inflammation & Immune System Conditions: Autoimmune Thyroid Conditions (Hashimoto’s & Graves’ Disease) |
| SLC18A1 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: Serotonin Imbalance |
| SLC23A1 |
| Reports: Nutrient Core Primary System: Other / Cofactors & Transport Conditions: Vitamin C Deficiency |
| SLC30A8 |
| Reports: Metals and Minerals Report Primary System: Other / Cofactors & Transport Conditions: Immune Dysfunction (Zinc Deficiency) |
| SLC39A8 |
| Reports: Metals and Minerals Report, Detoxification Primary System: Glutathione & Redox Conditions: Immune Dysfunction (Zinc Deficiency), Manganese Deficiency & Oxidative Stress |
| SLC6A2 |
| Reports: Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Anxiety, Depression & Low Mood, Migraine |
| SLC6A3 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: ADHD & Neurotransmitters, Addiction & Impulsivity, Dopamine Imbalance |
| SLC6A4 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: IBS (Irritable Bowel Syndrome) |
| SLCO1B1 |
| Reports: Thyroid Health Report Primary System: Thyroid Conditions: Thyroid Hormone Transport |
| SLCO1C1 |
| Reports: Thyroid Health Report Primary System: Thyroid Conditions: Thyroid Hormone Transport |
| SOD2 |
| Reports: Detoxification, Metals and Minerals Report Primary System: Glutathione & Redox Conditions: Manganese Deficiency & Oxidative Stress, Reactive Oxygen Species (Oxidative Stress) |
| SULT1A1 |
| Reports: Detoxification, Thyroid Health Report Primary System: Liver Conjugation Conditions: PAHs & Pollution Detox, Thyroid Hormone Metabolism & Detoxification |
| SULT1E1 |
| Reports: Detoxification, Hormones, Thyroid Health Report Primary System: Liver Conjugation Conditions: Oestrogen Dominance, Thyroid Hormone Metabolism & Detoxification |
| TCF7L2 |
| Reports: Nutrient Core, Hormones, APOE Primary System: Other / Cofactors & Transport Conditions: Insulin Resistance & Metabolic Syndrome, Sugar & Fat Metabolism |
| TCN2 |
| Reports: Methylation Report, Nutrient Core Primary System: Methylation Conditions: Methylation Efficiency & Homocysteine Management, Vitamin B12 Deficiency |
| TG |
| Reports: Thyroid Health Report Primary System: Thyroid Conditions: Autoimmune Thyroid Conditions (Hashimoto’s & Graves’ Disease), Thyroid Health (General & HPT Axis Regulation) |
| TH |
| Reports: Nervous System, Nutrient Core, Hormones Primary System: Neurotransmitters Conditions: Cognitive Function (Memory), Dopamine Imbalance, Hypertension |
| TPH1 |
| Reports: APOE, Detoxification, Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Depression & Low Mood, Gut Health (General), IBS (Irritable Bowel Syndrome), Serotonin Imbalance |
| TPH2 |
| Reports: APOE, Detoxification, Nervous System, Nutrient Core Primary System: Neurotransmitters Conditions: Depression & Low Mood, Gut Health (General), IBS (Irritable Bowel Syndrome), Serotonin Imbalance |
| TMPRSS6 |
| Reports: Metals and Minerals Report Primary System: Glutathione & Redox Conditions: Iron-deficiency Anaemia |
| TNF |
| Reports: APOE, Nervous System, Nutrient Core, Thyroid Health Report Primary System: Inflammation & Immune System Conditions: Alzheimer’s Disease (General Risk), Alzheimer’s Disease (Inflammatory subtype), Bowel Cancer Prevention, Chronic Inflammation (Neurological), Depression & Low Mood, Gut Health (General), Inflammation & Mood, Thyroid-Related Inflammation |
| TPMT |
| Reports: Detoxification, Nutrient Core, Hormones Primary System: Methylation Conditions: Poor Methylation |
| TRPM6 |
| Reports: Metals and Minerals Report Primary System: Other / Cofactors & Transport Conditions: Chronic Fatigue (Magnesium deficiency) |
| TRPV1 |
| Reports: Nervous System Primary System: Neurotransmitters Conditions: Anxiety, GABA Imbalance, Glutamate Imbalance, Migraine, Pain Sensitivity |
| TSHR |
| Reports: Thyroid Health Report Primary System: Thyroid Conditions: Autoimmune Thyroid Conditions (Hashimoto’s & Graves’ Disease), Thyroid Health (General & HPT Axis Regulation) |
| UGT1A1 |
| Reports: Detoxification, Thyroid Health Report Primary System: Liver Conjugation Conditions: Medication Detoxification & Sensitivity, NSAID Sensitivity, PAHs & Pollution Detox, Paracetamol Sensitivity, Pesticide & Chemical Sensitivity, Thyroid Hormone Metabolism & Detoxification |
| UGT1A6 |
| Reports: Detoxification Primary System: Liver Conjugation Conditions: Medication Detoxification & Sensitivity, NSAID Sensitivity, Paracetamol Sensitivity |
| VDR |
| Reports: APOE, Detoxification, Hormones, Nervous System, Nutrient Core, Thyroid Health Report Primary System: Other / Cofactors & Transport Conditions: ADHD & Neurotransmitters, Anxiety, Chronic Stress, Cognitive Decline & Neurodegeneration, Cognitive Function (Memory), Depression & Low Mood, Dopamine Imbalance, Hypertension, Migraine, Serotonin Imbalance, Sleep Disorders, Thyroid Hormone Activation, Thyroid-Related Inflammation, Vitamin D Deficiency |
| VKORC1 |
| Reports: Nutrient Core Primary System: Other / Cofactors & Transport Conditions: Vitamin K Issues |
