Reference Number: 178
Intolerance & Sensitivity: Coeliac
Background: Treatment of celiac disease (CD) is based on the avoidance of gluten-containing food. However, it is not known whether trace amounts of gluten are harmful to treated patients.
Objective: The objective was to establish the safety threshold of prolonged exposure to trace amounts of gluten (ie, contaminating gluten).
SIGNIFICANCE OF THIS STUDY
The allowable level of gluten contamination in products labelled as suitable for people with celiac disease varies from one country to another. This study investigates response shown by celiacs over a three month period to different levels of gluten intake. It found large variation in patient’s responses to gluten intake at different levels, and suggests this complicates the issue of setting uniform guidelines for maximum gluten contamination.