The Sourdough School

BREAD COURSES || NUTRITION TRAINING || DIGESTION ANALYSIS || PERSONALISED BREAD

Learn to bake, eat, and share the healthiest bread in the world. Discover how to bake as Lifestyle Medicine from the walled gardens of Dr Vanessa Kimbell’s beautiful Victorian home in rural Northamptonshire in the UK, where we train healthcare professionals, teach bakers, and support individuals to bake personalised bread using nutrigenetics and gut health assessments.

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282 - ‘Glutamine and the regulation of intestinal permeability: from bench to bedside’. Current Opinion in Clinical Nutrition and Metabolic Care. 20(1):86–91

Reference Number: 282

Year: 2017

Authors: Achamrah N., Déchelotte P. & Coëffier M.

Link: Link to original paper

Summary

Purpose of review
Glutamine is the most abundant amino acid in plasma and plays a key role in maintaining the integrity of
intestinal barrier.
Recent findings
Experimental studies showed that glutamine is able to modulate intestinal permeability and tight junction
protein expression in several conditions. Recent articles underlined its putative beneficial role in
gastrointestinal disorders such as irritable bowel syndrome.
Summary
Glutamine is a major nutrient to maintain intestinal barrier function in animals and humans. Depletion of
glutamine results in villus atrophy, decreased expression of tight junction proteins and increased intestinal
permeability. Moreover, glutamine supplementation can improve gut barrier function in several
experimental conditions of injury and in some clinical situations. Furthermore, preventive effects of
glutamine in experimental models of intestinal injuries have been recently reported. Despite promising data
in experimental models, further studies are needed to evaluate glutamine supplementation in clinical
practice.

 

What does this mean for bakers?

Glutamine is an important nutrient which helps to maintain the gut lining and create a barrier preventing pathogens crossing from the gut to the bloodstream. Foods rich in glutamine include animal proteins, fish, nuts, cabbage and beans, many of which can all easily be incorporated into our baking or eaten alongside baked goods.

Take a look at our courses at The Sourdough School

All reasonable care is taken when advising about health aspects of bread, but the information that we share is not intended to take the place of treatment by a qualified medical practitioner. You must seek professional advice if you are in any doubt about any medical condition. Any application of the ideas and information contained on this website is at the reader's sole discretion and risk.

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