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49 - ‘Oxidative stress and cardiovascular health: therapeutic potential of polyphenols.’. Can J Physiol Pharmacol. 91(3):198-212

Reference Number: 49

Year: 2013

Authors: Khurana S, Piche M, Hollingsworth A, Venkataraman K, Tai TC.

Link: Link to original paper

Health: Heart Disease

Nutrition: Polyphenols

Summary

Summary

Reactive oxygen species (ROS) are important in normal cellular function and physiology. However, oxidative stress resulting from an accumulation of ROS has a detrimental impact on cellular function, and ROS has been implicated in the pathogenesis of a number of diseases, including cardiovascular diseases. This review provides a summary of the impact of ROS on cardiovascular health and diseases, highlighting the therapeutic use of antioxidants. In addition, this review summarizes the health benefits of polyphenols, and the recent progress on understanding the cellular and physiological actions by which polyphenols may impart their beneficial properties on cardiovascular health.

 

SIGNIFICANCE OF THIS STUDY

The current review focusses on the role of polyphenols in cardiovascular health. The main antioxidant property of polyphenols (or the ability of polyphenols to mop up harmful molecules in our blood stream) provides these compounds to protect us from cardiovascular disease. Wholegrains are particularity rich in a range of polyphenols such ferrulic acid present in wheat and rye. Moreover, studies have shown the the process of sourdough fermentation and germination have the abilities to increases the overall  polyphenol content of these wholegrains thereby providing us with added health benefits.

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All reasonable care is taken when advising about health aspects of bread, but the information that we share is not intended to take the place of treatment by a qualified medical practitioner. You must seek professional advice if you are in any doubt about any medical condition. Any application of the ideas and information contained on this website is at the reader's sole discretion and risk.

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