The Sourdough School

BALM – Proven as one of the healthiest approaches to bread in the world.

Based in the walled gardens of Dr. Vanessa Kimbell's beautiful Victorian home in rural Northamptonshire, UK, we tutor individuals and train bakers and healthcare professionals in Baking as Lifestyle Medicine (BALM). Personalising bread to your lifestyle, gut microbiome, and unique genetics for optimal health—tailoring fermentation, fibre, and diversity so that your daily bread becomes the foundation of your health.

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67 - ‘Interaction between phenolics and gut microbiota: Role in human health’. J. Agric. Food Chem. 57 (15), 6485–6501

Reference Number: 67

Year: 2009

Authors: María V. Selma, Juan C. Espín and Francisco A. Tomás-Barberán

Link: Link to original paper

Health: Gut Microbiome - Creating Healthier Bread to Support Optimal Gut Health

Nutrition: Polyphenols

Summary

Summary

Dietary phenolic compounds are often transformed before absorption. This transformation modulates their biological activity. Different studies have been carried out to understand gut microbiota transformations of particular polyphenol types and identify the responsible microorganisms. Although there are potentially thousands of different phenolic compounds in the diet, they are typically transformed to a much smaller number of metabolites. The aim of this review was to discuss the current information about the microbial degradation metabolites obtained from different phenolics and their formation pathways, identifying their differences and similarities. The modulation of gut microbial population by phenolics was also reviewed in order to understand the two-way phenolic?microbiota interaction. Clostridium and Eubacterium genera, which are phylogenetically associated, are other common elements involved in the metabolism of many phenolics. The health benefits from phenolic consumption should be attributed to their bioactive metabolites and also to the modulation of the intestinal bacterial population.

 

SIGNIFICANCE OF THIS STUDY

Polyphenols are a class of health promoting simple or complex compounds that are present in plant based foods. Simple polyphenols are more easily absorbed in the small intestine following consumption. However, complex polyphenols need to be broken down by specific microbes present in the large intestine or colon. Metabolites (substances formed during the breakdown/metabolism) of food polyphenols play an important role in the health benefits of fruits and vegetables. Many complex dietary phenolics undergo similar transformations (i.e broken down) in the gut by means of microbial enzymes and release the simpler, easily absorbable compounds, which may then be directly absorbed into the blood stream from the colon. This could probably explain some common health benefits observed after the intake of foods with very diverse phenolic compositions. The degree of degradation however of many phenolic compounds is significantly influenced by the amount of phenolic compounds present in the diet as well as individual variations in the composition of the colonic microbiota. This could be the reason why there exists large inter-individual variability in the health benefits observed, which has been attributed to dissimilarities in the populations and type of microbes present in the colon. This paper therefore suggests that it is important to have a better understanding of the dietary phenolic and gut microbiota relationship which could help in the prevention of intestinal diseases, such as inflammatory bowel diseases and colon cancer, as well as in improvement of human health avoiding other chronic diseases.

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All reasonable care is taken when advising about health aspects of bread, but the information that we share is not intended to take the place of treatment by a qualified medical practitioner. You must seek professional advice if you are in any doubt about any medical condition. Any application of the ideas and information contained on this website is at the reader's sole discretion and risk.

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