The Sourdough School

Baking eating and sharing bread to improve physical and mental health

Using a robust evidence-based baking protocol combining the evidence of thousands of years of baking with modern clinical insights, we offer comprehensive training to bakers and healthcare professionals, providing students with the tools to use baking in everyday practice as a wellness intervention.
Follow on Instagram

Soil Association
Our gardens are certified organic.

Baking as Lifestyle Medicine for Bakers and Clinicians

+44(0)7707 480336
[email protected]
Follow on Instagram
  • Facebook
  • Instagram
  • Pinterest
  • Twitter

Student Login

Navigation
  • Home
    • Login
  • About us
    • The School
    • Contact Us & FAQ
    • The Team
    • Contributors & Guest Tutors
    • General FAQ’s about The School
    • Be the Change
  • Admissions
    • Courses
    • Course Q&A’s
    • Graduation Week in Tuscany
    • Educational Awards Programme
    • Enrolment
    • Reviews
    • Student Welfare
    • Policies & Compliance
  • The Certificate
    • The Certificate
    • Teaching
    • Teacher Training
  • The Diploma
    • The Diploma
    • Licence to Prescribe BALM
  • BALM
    • Baking as Lifestyle Medicine
    • What is BALM?
    • BALM & Bread in The Blue Zone
    • Case Studies Library
    • BALM Podcasts
  • Shop
    • Books
    • Equipment
    • Ingredients

81 - ‘The Gut Microbiome Feelings of the Brain: A Perspective for Non-Microbiologists’. Microorganisms. 12;5(4)

Reference Number: 81

Year: 2017

Authors: Lerner A, Neidhöfer S, Matthias T

Link: Link to original paper

Health: Gut Microbiome - Creating Healthier Bread to Support Optimal Gut Health | Mental Health

Summary

Summary

To comprehensively review the scientific knowledge on the gut-brain axis. Various publications on the gut-brain axis, until 31 July 2017, were screened using the Medline, Google, and Cochrane Library databases. The search was performed using the following keywords: “gut-brain axis”, “gut-microbiota-brain axis”, “nutrition microbiome/microbiota”, “enteric nervous system”, “enteric glial cells/network”, “gut-brain pathways”, “microbiome immune system”, “microbiome neuroendocrine system” and “intestinal/gut/enteric neuropeptides”. Relevant articles were selected and reviewed.

Results: Tremendous progress has been made in exploring the interactions between nutrients, the microbiome, and the intestinal, epithelium-enteric nervous, endocrine and immune systems and the brain. The basis of the gut-brain axis comprises of an array of multichannel sensing and trafficking pathways that are suggested to convey the enteric signals to the brain. These are mediated by neuroanatomy (represented by the vagal and spinal afferent neurons), the neuroendocrine-hypothalamic-pituitary-adrenal (HPA) axis (represented by the gut hormones), immune routes (represented by multiple cytokines), microbially-derived neurotransmitters, and finally the gate keepers of the intestinal and brain barriers. Their mutual and harmonious but intricate interaction is essential for human life and brain performance. However, a failure in the interaction leads to a number of inflammatory-, autoimmune-, neurodegenerative-, metabolic-, mood-, behavioral-, cognitive-, autism-spectrum-, stress- and pain-related disorders. The limited availability of information on the mechanisms, pathways and cause-and-effect relationships hinders us from translating and implementing the knowledge from the bench to the clinic.

 

SIGNIFICANCE OF THE STUDY

Further understanding of this intricate field might potentially shed light on novel preventive and therapeutic strategies to combat these disorders. Nutritional approaches, microbiome manipulations, enteric and brain barrier reinforcement and sensing and trafficking modulation might improve physical and mental health outcomes.

Qualify in Baking as Lifestyle Medicine

All reasonable care is taken when writing about health aspects of bread, but the information it contains is not intended to take the place of treatment by a qualified medical practitioner. You must seek professional advice if you are in any doubt about any medical condition. Any application of the ideas and information contained on this website is at the reader's sole discretion and risk.

  • Facebook
  • Instagram
  • Pinterest
  • Twitter

Email Sign Up

Terms and Conditions | Privacy Policy
Copyright © 2023 Vanessa Kimbell
Call +44 (0)1604 881274 | Email [email protected]
Registered in England & Wales: 08412236
Website by Callia Web