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443 - ‘Citrus fruits and their flavonoids in inflammatory bowel disease an overview’. Natural Product Research. 34(1): 122-136

Reference Number: 443

Year: 2020

Authors: Laura Musumeci, Alessandro Maugeri, Santa Cirmi, Giovanni Enrico Lombardo, Caterina Russo, Sebastiano Gangemi, Gioacchino Calapai, Michele Navarra

Link: Link to original paper

Flavour: Aldehydes>Fruity

Health: Cardiometabolic diseases | Gut Microbiome - Creating Healthier Bread to Support Optimal Gut Health | Inflammation | Inflammatory bowel disease | Lower Inflammation

Nutrition: Flavonoids | Prebiotic | Vitamins

Summary

Inflammatory bowel disease (IBD), with its major manifestations being Crohn’s disease and ulcerative colitis, belongs to the gastrointestinal inflammatory disorders, whose main therapeutic approach is represented by synthetic anti-inflammatory drugs. However, they are often accompanied by many side effects that shifted the interest of the scientific community towards natural products. In this context, several studies asserted the anti-IBD effects of Citrus fruits and their flavonoids, thus the aim of the present review is to provide robust evidence favouring their role in the prevention and treatment of IBD. Key mechanisms relate to their anti-inflammatory and antioxidant properties, as well as their ability to modulate gut microbiota. All the findings collected in this review, lay the foundations for further studies in human with the aim of evaluating the concrete applicability as a novel preventive and therapeutic approach of Citrus fruits and their flavonoids.

Significance to the baker:

This study indicates that the use of citrus in our bakes may boost the content of favourable bioactive compounds that may not only work to ease symptoms inflammatory bowel disease (IBD) but may also provide us with further health benefits by feeding the beneficial bacteria in our gut.

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All reasonable care is taken when advising about health aspects of bread, but the information that we share is not intended to take the place of treatment by a qualified medical practitioner. You must seek professional advice if you are in any doubt about any medical condition. Any application of the ideas and information contained on this website is at the reader's sole discretion and risk.

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